Cold Spring Harbor Laboratory is holding the “Statistical Analysis of Genome Scale Data” advanced course from June 30 – July 13, 2023. Vincent Carey from Harvard Medical School and Sean Davis from the University of Colorado Anschutz School of Medicine will instruct the class with the help of invited guest speakers. The class will focus on building competence in statistical methods and analyzing high-throughput data in genomics and molecular biology through lectures and hands-on computer tutorials.
Topics will include:
- The R environment for statistical computing and graphics
- Introduction to Bioconductor
- Review of basic statistical theory and hypothesis testing
- Experimental design, quality control, and normalization
- High-throughput sequencing technologies
- Expression profiling using RNA-Seq and microarrays
- In vivo protein binding using ChIP-Seq
- High-resolution chromatin footprinting using DNase-Seq
- DNA methylation profiling analysis
- Integrative analysis of data from parallel assays
- Representations of DNA binding specificity and motif discovery algorithms
- Predictive modeling of gene regulatory networks using machine learning
- Analysis of post-transcriptional regulation, RNA binding proteins, and microRNAs
Visit the course website for more information, including information on stipends to offset tuition costs.
Statistical Analysis of Genome Scale Data, CSHL June 30 – July 13