Center for Sorghum Improvement seminar:
SorghumBase: Building A Comprehensive Resource for the Sorghum Community
Tuesday, October 29 11:00 a.m. CT
Nick Gladman USDA-ARS Research Molecular Biologist
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Nick Gladman began his plant research journey by obtaining his Ph.D in Genetics from the University of Wisconsin-Madison in 2015, which focused on Arabidopsis regulatory networks governing protein turnover. He then switched to working with sorghum as a postdoc with the USDA in Lubbock, TX and then transitioned to a postdoctoral fellowship at Cold Spring Harbor Laboratory, NY before rejoining the USDA as a permanent scientist in 2022. Currently, his research goals have been geared toward uncovering gene modules that control inflorescence development and nutrient use efficiency, the genomics of sorghum quality traits, and contributing to community resource development with the SorghumBase team.
Abstract: SorghumBase (https://www.sorghumbase.org) is a USDA-ARS funded resource for curated multi-omic and genetic data sets in sorghum. SorghumBase works closely with the community to support stewardship of sorghum genomics data, while establishing best-practices on data management and coordination with the community. We maintain a database of scientific publications, genome sequences, gene structure annotations, and comparative genomic analyses integrated with curated data from the Gene Expression Atlas at EBI, Plant Reactome pathway database, and QTL Atlas at OZ Sorghum. The community coordination aims to improve reference structural gene annotations and develop standards for nomenclature and support through FAIR (Findable, Accessible, Interoperable, Reusable) practices with genetic variation data. We have worked with sorghum researchers, producers, and service providers to develop a marker panel for breeding and molecular biology programs. In addition, weekly news items related to sorghum include highlights on recent publications, conferences, and community events. Our outreach activities include user guides and training sessions. SorghumBase offers sorghum investigators improved data collation and exposure that will aid in building an even more robust research community in support of genomics assisted breeding. Supported by USDA-ARS #8062-21000-051-000D.