Integrative Molecular and Physiological Mechanisms Underlying Drought Tolerance in Sorghum

Drought tolerance in sorghum arises from coordinated molecular, biochemical, and physiological mechanisms, including elevated osmoprotectant levels, enhanced antioxidant defenses, and activation of ABA-dependent bZIP transcription factors that collectively maintain cellular stability and promote resilience under water stress.

Stem-Preferred Gene Regulation and Meristematic Origins Underlying Transcriptional Specificity in Sorghum

A genome-wide analysis of sorghum revealed that stems possess relatively few organ-specific genes due to their meristematic origins, with two KNOX-like transcription factors, SbTALE03 and SbTALE04, emerging as key stem-preferred regulators and promising tools for targeted engineering supported by regulatory and network evidence.

Rp2: A Novel Rust Resistance Locus from Sudanese Sorghum for Broadening Genetic Diversity in U.S. Breeding Programs

By unlocking rare, evolutionarily conserved rust resistance locus from the Sudanese sorghum core collection, this work bridges global germplasm diversity with modern breeding, revealing Rp2 locus is a tractable genomic entry point for stacking durable, multi-disease resistance and strengthening the genetic resilience of U.S. sorghum improvement.

Genetic Architecture and Co-Localized QTL Underlying Plant Height and Brix Content in Sorghum

Genetic modeling and high-density QTL mapping reveal that sorghum plant height and brix content are governed by interacting major genes and polygenes, share co-localized loci that explain their phenotypic correlation, and are influenced by auxin- and carbon-fixation–related candidate genes that offer targets for breeding improved varieties.