A genome-wide association study of sorghum seedlings under salt stress identified 35 loci and 39 candidate genes—many conserved across species—implicated in salt sensing, ROS detoxification, osmotic adjustment, and K⁺/Na⁺ homeostasis, providing targets for improving salt tolerance through molecular breeding.
SbHMA5-Mediated Copper Efflux and Metallochaperone Interactions Regulate Copper Homeostasis in Sorghum
SbHMA5 is a conserved P1B-type copper ATPase in sorghum that maintains copper homeostasis by interacting with metallochaperones to efflux excess Cu from the cytosol, thereby protecting plant growth and development from copper toxicity.
Heme-Dependent Dimerization and ER Membrane Remodeling by the Sorghum Membrane Steroid Binding Protein SbMSBP1
SbMSBP1 is an ER-localized MAPR protein in sorghum that binds heme, undergoes heme-dependent dimerization, and promotes membrane remodeling, suggesting roles in vesicle trafficking, cytochrome P450 stabilization, and stress-adaptive specialized metabolism.
Integrated Morphological, Physiological, and Transcriptional Mechanisms Underlying Waterlogging Tolerance in Sorghum
The sorghum genotype ‘S208’ exhibits superior waterlogging tolerance through coordinated activation of anaerobic energy metabolism, hormone signaling, and cell wall remodeling that drives adventitious root formation and aerenchyma development under hypoxic conditions.
Engineering Synthetic Apomixis to Enable Clonal Hybrid Seed Production in Sorghum
Synthetic apomixis was successfully engineered in hybrid sorghum, enabling clonal seed formation that preserves hybrid heterozygosity across generations, although further optimization is needed to improve fertility and developmental stability.
Conserved and Dynamic Gene Regulatory Networks Underlying Nitrogen Use Efficiency in Cereal Crops
Conserved gene regulatory networks underpin nitrogen metabolism across plants, with dynamic and species-specific rewiring in maize and sorghum during rapid nitrogen deprivation and recovery, revealing key transcriptional regulators that shape nitrogen use efficiency and sustainable crop productivity.
Integrative Molecular and Physiological Mechanisms Underlying Drought Tolerance in Sorghum
Drought tolerance in sorghum arises from coordinated molecular, biochemical, and physiological mechanisms, including elevated osmoprotectant levels, enhanced antioxidant defenses, and activation of ABA-dependent bZIP transcription factors that collectively maintain cellular stability and promote resilience under water stress.
Salt-Tolerant Phosphorus-Solubilizing Fungi Enhance Nutrient Availability and Plant Performance in Saline Soils
Salt-tolerant phosphorus-solubilizing fungi enhance plant nutrition and stress resilience in saline soils through organic acid–mediated P mobilization, antifungal metabolite production, and adaptive physiological mechanisms, highlighting their potential as biofertilizers pending field validation.
Integrated Cytological and Multi-Omics Analysis Reveals Phenylpropanoid-Mediated Regulation of Leaf Angle Formation in Sorghum
Leaf angle formation in sorghum is driven by coordinated changes in auricle cell development, phenylpropanoid-mediated lignin biosynthesis, and associated gene expression, collectively shaping plant architecture for improved light capture.
Stem-Preferred Gene Regulation and Meristematic Origins Underlying Transcriptional Specificity in Sorghum
A genome-wide analysis of sorghum revealed that stems possess relatively few organ-specific genes due to their meristematic origins, with two KNOX-like transcription factors, SbTALE03 and SbTALE04, emerging as key stem-preferred regulators and promising tools for targeted engineering supported by regulatory and network evidence.